Select Publications


Davenport, MP, Smith, NL, Rudd, BD. Building a T cell compartment: how immune cell development shapes function. Nat Rev Immunol (2020).

Rudd BD. Neonatal T Cells: A Reinterpretation. Annu. Rev. Immunol. 2020. 38:229–47 doi: 


Tabilas C, Wang J, Liu X, Locasale JW, Smith NL, Rudd BD. Cutting Edge: Elevated Glycolytic Metabolism Limits the Formation of Memory CD8+ T Cells in Early Life. J Immunol. 2019 Oct 9. pii: ji1900426. doi: 10.4049/jimmunol.1900426.

Yee Mon KJ, Goldsmith E, Watson NB, Wang J, Smith NL, Rudd BD. Differential Sensitivity to IL-12 Drives Sex-Specific Differences in the CD8+ T Cell Response to Infection. ImmunoHorizons. April 1, 2019, 3 (4) 121-132

Reynaldi A, Smith NL, Schlub TE, Tabilas C, Venturi V, Rudd BD, Davenport MP. Proc Natl Acad Sci U S A.  2019 Feb 14. pii: 201811634. https://doi: 10.1073/pnas.1811634116.


Smith NL, Patel RK, Reynaldi A, et al. Developmental Origin Governs CD8 T Cell Fate Decisions during Infection. Cell. 2018;174(1):117-130.e14.


Wang J, Wissink EM, Watson NB, Smith NL, Grimson A, Rudd BD. Fetal and adult progenitors give rise to unique populations of CD8+ T cells. Blood. 2016;128(26):3073-3082.

Reynaldi A, Smith NL, Schlub TE, Venturi V, Rudd BD, Davenport MP. Modeling the dynamics of neonatal CD8(+) T-cell responses. Immunol Cell Biol. 2016;94(9):838-848.

Venturi V, Nzingha K, Amos TG, et al. The Neonatal CD8+ T Cell Repertoire Rapidly Diversifies during Persistent Viral Infection. J Immunol. 2016;196(4):1604-16.


Smith NL, Wissink EM, Grimson A, Rudd BD. miR-150 Regulates Differentiation and Cytolytic Effector Function in CD8+ T cells. Sci Rep. 2015;5:16399.

Wissink EM, Smith NL, Spektor R, Rudd BD, Grimson A. MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells. Genetics. 2015;201(3):1017-30.

Cohen SB, Smith NL, Mcdougal C, et al. Beta-catenin signaling drives differentiation and proinflammatory function of IRF8-dependent dendritic cells. J Immunol. 2015;194(1):210-22.

Smith NL, Wissink E, Wang J, et al. Rapid proliferation and differentiation impairs the development of memory CD8+ T cells in early life. J Immunol. 2014;193(1):177-84.